Illustration concrète de la procédure que j'ai partagée dans un billet précédent: comment transcrire le texte d'une vidéo, en automatique

J'ôte juste en automatique les retours de ligne. Il s'agit du texte de la vidéo Bullseye sur la LDN.

On verra ici qu'il faut encore un peu de boulot pour en faire une lecture ou même le proposer à un traducteur automatique. Mais cet état me suffit pour indexer le contenu sur mon disque dur, alors que la recherche dans une vidéo YT est impossible. Si l'intention est de s'économiser du temps de vidéo, c'est loupé, car même une lectrice hyperrapide comme moi (et bilingue) ne gagne pas de temps à lire sous cet état-là. Comment je sais? Ben j'ai testé!

Le texte brut

  there's common     agreement in the medical world that Lyme disease exists in fact the CDC now estimates there may be as many as     300,000 new Lyme infections a year in the u.s. in school it's horrible because     I will sit through class and just zone out and then after class I don't even know what just happened     campaigners have called it one of the most dangerous illnesses to threaten mankind today but it's thought thousands     of people are living with a disease which goes undiagnosed the number of cases has been increasing most were     concentrated in the Northeast ninety six percent of them in 13 states so oft is     Lyme disease and where does it come from and how does it cause so much damage to so many people and can low dose     naltrexone help to combat this epidemic I started my journey by traveling to     Poughkeepsie in New York State to visit dr. Richard Horowitz there's no doubt in     my mind this is probably one of the most intelligent bacteria on the planet in fact it has three times more DNA than     any of its closest relatives which would be chlamydia pneumonia this organism knows how to evade the     immune system it knows how to hide inside cells it has decoy mechanisms to     protect itself from the immune system it knows how to shift its outer surface proteins so it fools the immune system     and finding it it's a very clever bacteria so there definitely is an intelligence of this bacteria it's been     around for millions of years they discovered it in amber specimens actually years ago and a Nazi who was     the Neanderthal man who was found in tyrolia so the bacteria has been around for a long time but I don't think people     have recognized the full clinical manifestations of causing fatigue and     arthritis and memory problems yet the bacteria has been around for quite a long time well like any new disease     there are always two camps who debate the existence of a disease and how to diagnose and treat it and in this case     the two camps are the infectious disease Society of America and islets the International Lyman associated diseases     Society of which I was one of the founding members so when lime was discovered     approximately 40 45 years ago in Lyme Connecticut by dr. Allen Steere he's a     Rheumatologist and he did an excellent job discovering the bacteria but he thought because people failed 1 or 2 weeks of     antibiotics that it was an autoimmune disease and then the infectious disease doctors got ahold of it and there was     funding from the NIH that they got on this and they also felt that it was mainly autoimmune or they just didn't     understand why people stayed chronically ill so over time the debate has developed where we now know in fact that     the blood test to diagnose this disease are very unreliable we miss approximately half the patients it's     like a coin flip using the standard test of an Eliza one of the tests in Europe that's also used in the u.s. called the     c6 Eliza it's a bit better because it also checks for European strains so     there are a hundred strains of Lyme disease in the United States and 300 strains worldwide and in Europe Borrelia     ABS Li and Borrelia garena are two of the major forms of Borrelia that exist in Europe and as Li causes a skin rash     called Accra dermatitis chronic Khmer trophic hands it's a violaceous skin rash of the hands and feet and Borrelia     green eye causes neuro Berlioz's or neurological problems with Lyme this new test the c6 Eliza will pick up these     other strains of Lyme so a lot of the doctors when they don't find it they're using an outdated form of an Eliza it is     much better in my opinion to use the c6 Eliza and to also use a Western blot with a laboratory that looks at several     different strains of Lyme it's become a taboo subject because there's a political aspect to this disease it's     not just a medical disease so for example in the United States doctors licenses have been taken away for     diagnosing and treating this medical boards have come after doctors fortunately in New York State right practice the governor signed a bill     about two years ago protecting doctors in New York State for diagnosing and treating it there are other states that     have followed but unfortunately in Europe for example in France I know doctors who had their license taken away     and many doctors are scared to treat this disease because European governments and     many other governments Australia they're using CDC guidelines and the problem is     is that the CDC said on their website that Lyme disease is a clinical diagnosis you're only supposed to use     the tests for making a clinical diagnosis but the insurance companies took this definition and they told     doctors this was the only way to diagnose it so many doctors are thrown out of insurance companies for not     following the insurance company guidelines there are conflicts of interest of some of the members of the     infectious disease Society of America some of them do make money from some of the Lyme tests and they've been getting     funds from the NIH for quite a long period of time to hold their same viewpoint which is that it's an     autoimmune phenomenon there's damage to the body or we just don't know why people are sick except in the middle of     a number one worldwide spreading epidemic it's just not acceptable to say we don't know why these people are     staying ill so in 2013 the CDC revised their estimates and they said that there     was a tenfold increase in the number of Lyme cases from 30,000 to over 300,000     cases a year however we know that they are not counting the people who have been diagnosed with chronic fatigue     syndrome which is three and a half percent of the American population fibromyalgia which is 1.5 percent of the     American population so they're alone you're dealing with millions of people that may have lyme disease because the     way you make the diagnosis of chronic fatigue and fibromyalgia and pains they     have sleep disorders they have memory problems and their autonomic nervous system the part of their nervous system     that controls the blood pressure is thrown off well you see that with chronic fatigue with fibro and with Lyme     so the numbers I think are grossly underestimated I suspect there's probably at least one to two million     people a year getting Lyme disease in the United States the World Health Organization has shown that there's     millions of people across especially Western Europe that are getting Lyme disease in the Balkan countries and we     know in China that up to 6% of the Chinese population has had and been exposed to Lyme and I know that because     I met with the head of the CDC in China the Chinese government invited me over as a consultant and told me privately     that those were the numbers which would mean six percent of one point four billion people you're dealing with     5060 million people you're dealing with huge numbers of people who have Lyme disease in 2015 the CDC then revised the     estimates and said that there was a three hundred and twenty percent increase in the number of counties     affected in the United States that it was spreading in all directions so because the blood tests are unreliable     the iliza will only pick up approximately half the people and the fact that the insurance companies have     adopted the eliza followed by a western blood which is what the CDC uses to     epidemiologically screen large numbers of people we find that the insurance companies are not really adequately     diagnosing these people and therefore instead of getting to the source of the illness they're just allowing their     doctors to give these people medication to treat their pain they may take aricept patches and namenda for their     memory problems they may take anti-inflammatory medicines and neurontin for their neuropathy and their     pain but they're not getting to the underlying source and I suspect that they think they may be saving money doing this because the insurance     companies at this point are suffering in the United States our health care system is certainly in disarray at this point     and I think that we do need an overhaul of the way we do practice chronic disease medicine but I do think the     insurance companies they know there are two guidelines for treating Lyme and they have chosen the guideline that     basically says that very few people get this disease and need to be treated so I think that needs to be addressed from a     political issue and hopefully the 21st century cure act got passed in Congress just this past year hopefully we'll have     better answers for Lyme which the insurance companies will adapt in the next couple of years doctors need to be     aware of this disease because it is going to affect the future generations of America for example mothers can     transmit Lyme disease as well as other tick-borne infections like Babesia Rocky Mountain spotted fever Bartonella these     can all be transmitted to the fetus and I know for a fact that OBGYNs generally     are not screening women for Lyme disease and tick-borne disorders before they get pregnant if they would use the     questionnaire that's in my book as a simple screening tool they would see that these women have a multi systemic     illness they're tired they're achy they have a headache the key to Lyme disease however is     migratory pain migratory joint pain migratory muscle pain migratory nerve     pain if OBGYNs were to ask these questions they'd be able to see if a woman about to get pregnant has Lyme or     a psychiatrist who has a patient come in and say I'm depressed I'm anxious I have     obsessive-compulsive disorder I'm schizophrenic Lyme causes every neuropsychiatric manifestation that     psychiatrist see a psychiatrist would want to hand out this questionnaire to see if they have a multi systemic     disorder so because Lyme will affect the heart the cardiologists need to be     looking into it right there we had a young man in Poughkeepsie years ago who came back from Rhode Island and he had a     flu-like illness the doctor checked him for Lyme the test was negative and he died three weeks later from Lyme     carditis there's definitely an urgency to diagnose this disease because if you can get it within the first 30 days you     can cure it so we know that 75 to 80 percent of the people if they happen to see the bullseye rash and by the way     half of the rashes look like bull's-eyes and half of the rashes are solid spreading rashes but 50% of the people or more at least     in the United States do not get the rash but if you do find the rash or see a tick bite and get sick and you treat it     for example with doxycycline or Sefton in the first 30 days you can cure it however those people who are not so     lucky who go past 30 days those usually the ones who come to my medical practice who have long term problems they've been     to 10 to 20 doctors looking for answers and by the time they come to see me many of them are disabled so it's very     important that people follow a sugar-free yeast-free diet because when you're giving antibiotics you can affect     an overgrowth of yeast and the colon and also could cause diarrhea so the first thing we do is we tell people to stay     off all sugar many of them do well off gluten you have to check if they have food sensitivities because the thing     about Lyme disease is the symptoms of Lyme disease are due to inflammation in the body there are molecules called     inflammatory cytokines TNF alpha il-1 il-6 interferon gamma these are the     molecules that cause people to be sent with Lyme if you have food allergies like if you're sensitive to gluten or if     you're allergic to dairy or wheat you're going to get the same molecules produced just like you do with     lime so in the 16 point M SIDS model that I use 8 out of the 16 points caused     inflammation so these people have to get to sleep if you don't get to sleep at night you have too much inflammation too     much intial luke and 6 is produced if you're eating the wrong foods right if you have the wrong bacteria in the     microbiome of your gut you can have inflammation if your mineral deficient like zinc deficiency will cause     increased inflammation in the body so we give high dose probiotics over 300     billion of good quality probiotics with Saccharomyces boulardii to stop c-diff diarrhea we have people on a regular     exercise program getting them to sleep and then we use things like low dose naltrexone low dose naltrexone has been     published in the medical literature for multiple sclerosis for crohn's disease for fibromyalgia and we've used it in     over a thousand people with Lyme and we find it to be very effective in fact my wife is still on LDN after getting over     lyme disease and she finds it to be very very useful the reason LDN works and the reason we     use nutritional supplements with LDN is LDN will block certain cells in the     brain called microglial cells these are these small glial cells in the brain that cause inflammation and those are     the cells that have been responsible for the manifestations of Alzheimer's disease and other neurodegenerative disorders they're the same cells that     cause inflammation in patients with Lyme disease so LDN will shut down this     microglial proliferation of making cytokines it helps to shift some of the     cytokine formation in the body so this last 2-minute Krause is factor-alpha less interleukin 6 and the way it does     this is there is a switch inside the nucleus of the cells called NF kappa-b so if you can shut off this switch     inside your cells called NF kappa-b which l DN does and other things that do     it for example our nutritional supplements like curcumin green tea extract broccoli seed extract     resveratrol these are the four supplements that we use with LDN that     tell this particular switch inside the nucleus to turn off shuts down the     production of these inflammatory molecules and people feel tremendously so LDN and using these nutritional     supplements to help decrease the inflammatory response is part of the regular protocol that we use for people     who are chronically ill with Lyme disease my journey took me back to Europe in the ancient city of Antwerp in     Belgium to meet Paul desaad earlier a compounding pharmacist and a European chair of eyelids of course the treatment     of one is it is a complicated treatment     because the approach should be an integrative approach and this is     basically in my opinion the biggest     challenge in Europe when I compared the situation with the situation in America     I have a feeling that much more medical doctor GPS in America are using the     integrative approach functional medicine much more than in Europe and especially     in treatment of Lyme its multi-systemic disease you need integrative approach     because the pathogen is causing an immune dysfunction but is also     disrupting or detoxification is damaging     our mitochondria is impairing our     cognitive and memory functions is often     causing get hyper permeability so you have the different the multi-systemic     aspects of this multi infection and the only way especially in the chronic the     persistent cases to be successful in your treatment is to have this     integrative approach so if we educate doctors on Lyme treatments it's not only     an education on the level of what kind of pathogens bacteria via     are we dealing with it's also on the level of what is functional integrative     medicine so and this is its big     challenge it's a a big distance we have     we have we have to cover but let's let's     see it in a positive way if we compare the situation as it is now with for     example five years ago I see much more doctors were motivated who are involved     who follow conferences I want to learn more or interact so we definitely move     forward but of course on the other end I see also more and more aligned patients so it's it's of course it's     it's very time sensitive but with     education educational sessions the conference's we organize more and more     doctors should be able to treat patients and to cure wine patients even if it's a     big challenge often doctors ask me what are the possibilities well LDN is one of     the possibilities basically I think we have to order studied possibilities     transfer factors and glutathione transfer factors because they also     restore the communication between t-cells what leads to a better th1     response and a more balanced th1 th2 response angry the theone also the Theon     very important in lime restoring or     improving the toxification also very powerful antioxidant because we create a     lot of oxidative stress in lime but on top of that with a Theon is also improve     being our natural killer cell activity so I think in our integrative approach     in our total approach the immune party's is a very important part I have the     feeling that in the early stages when we were searching for solutions for Lyme we     focused toward on the antibiotic anti     bacterial or anti pathogen we needed to     use and based on experience based on the     results in our patients we realized that     we needed something more especially for the immune part and I think just for     that reason LDN is is a molecule that every doctor     should consider at some point in treatment in many different parts of     Europe still not accepted especially in Scandinavia we see that doctors lose     their license just by applying the guidelines and prescribing for example     antibiotics so it's really tough in indeed in some parts of Europe but we     need to find a global solution for that and so based on a situation how it is     now in France we would like to improve the total European acceptance and     situation especially of the patients     [Music] so what about getting better from Lyme     disease I traveled to California to meet three doctors who all treat Lyme patients successfully it's hard to say     exactly how many people that I have in my practice that I'm treating with Lyme     but recently I started using some different testing methods and I would     say probably in the last couple of months I've picked up maybe ten patients in my caseload that are actually testing     positive for Lyme now so I think that it might be skewed toward thinking it's     more women because probably I have a lot more women in my practice I think women certainly manifest a lot more immune     symptomatology than then men in general is kind of what we've seen historically     but I also think women are more likely to come in for treatment and more open     to discussing some of these symptoms that other people think are crazy it's incumbent upon us to support the immune     system so many people get Lyme and they're able to clear it they get a     slight infection they might feel like they have the flu over the weekend and their immune system takes care of it and     those aren't the people we have to worry about but we have some people that have loading genetically they might have a     genetic HLA type the HLA dr that makes them susceptible to developing chronic     lyme with an infection they may have problems with their GI system their diet     their gut might not be working well and of course most of our immune system is in our gut 60 percent is in the gut so     if people have GI problems that our immune system already is going to be compromised and so people with various     other factors happening are the ones that will get into trouble with chronic Lyme so the first thing that I do is     work with their diet I mean if people are not eating well if you know food has     the power to you know turn on good genes and turn on bad genes and so if people     aren't eating well there's no way that we can support their immune system to get better so that's the first place     that we start what are you eating and work with the diet and then work with the health of the gut so     I do testing in all my patients at the first visit I do comprehensive stool     analysis testing and I look for bacterial overgrowth yeast overgrowth parasites what are their inflammatory     markers how are they digesting their food you know what are their basic probiotic levels there and and so to me     that's kind of the first level I also look at nutrient levels there's various nutrients magnesium zinc some of the B     vitamins that all affect how the immune system works so trying to bring all those things into balance are going to     be my first way that I work with treating people with any kind of infection well it's pretty amazing with     the diet some people can come in to me with say a severe depression and I     couldn't take out the inflammatory foods take out the gluten and take out the dairy get them on a Whole Foods diet     just work with some basic nutrients and I can have people that are crying all day long and suicidal that will in short     order just be completely normal it's really important in my mind to take out     in foods that are inflammatory so anything that's inflaming the gut is     going to compromise the immune system so for me it's very important to ask people     to take out gluten we have plenty of data that that's a very inflammatory food we it's been modified it's it's not     been genetically modified but it's been hybridized so that it contains more and more gluten and we just don't seem to     digest that anymore and so it doesn't matter to me if people are allergic or not it's just going to compromise their     gut function and if I want to heal their immune system I need to start by healing their gut so that's kind of my line in     the sand I ask all patients to stop the gluten some patients I asked them to stop all grains especially those with     neurodegenerative symptoms the grains have been implicated in in affecting the     brain in many ways another important factor with the grains is the sugar content so they're very high in sugar     the glycine anacs is 20 percent higher than table sugar with wheat and so one important     part of settling down someone's immune system there's so many factors you have to look at all the factors that are out     of balance and for a lot of people it's their blood sugar regulation so many people have pre-diabetes that I'm seeing     and so eliminating the grains helps to regulate the blood sugar the dairy for     some people is inflammatory itself a second most common food allergy that we     have we know it elevates insulin growth factor one which is implicated in     cancers and other inflammatory disorders so especially for people that have     problems with sinus allergies that give me a history of early ear infections and     throat infections those are people I like to stop the dairy with as well I do believe that in in large degree were in     the midst of an epidemic that you know there we know that you know in the in the US alone there's probably at least     300,000 new cases every year of Lyme disease and those are CDC numbers which     were upgraded from a previous estimate of around 30,000 and they you know so     the number of 300,000 is you know still thought to be possibly conservative you     know so there might be a much larger number of new cases every year and you     know some of those cases I would say actually you know probably more than half of those people if you if you get     Lyme disease and you're treated with normal recommended course of two to three weeks of antibiotics     you know most of people go on to be fine and and not have long term symptoms but     we're getting better and better understanding and better data to point at the fact that there is a significant     subset of people who do go on to have chronic symptoms you know I feel like in     the last three to four years that were kind of over the tipping point of you     know whether or not this thing is real if you will and you know we're still not     seeing unfortunately we're still not seeing the funding that we need on the administrative or government     sides etc you know when you have these patients that are have have cases that     again don't seem to fit into any one box and span multiple different body systems     symptoms coming and going so again the index of suspicion when they arrive is     higher and that's important because again I think is actually fairly common     to be exposed to some of these pathogens and so some of the problems with the potential testing is that you could have     somebody who's relatively symptom free who might show some markers positive on the testing so you really have to put     testing together with the clinical picture so there was actually a good     study that came out of the UK a meta-analysis this past year that showed     that the sensitivity of Lyme disease testing is hovering a little bit above 50% so almost as good as a flip of a     coin basically and so the chances you know sensitivity basically the chance is that if the test says you don't have the     disease the chances that that test is wrong is around 50% so the tests miss a     lot of people and so again it's very important at that point to combine the whole story understand you know what the     what the potential risk is is has this person had documented tick bites have they been in in Lyme endemic areas which     unfortunately is many parts of the world so that's not hard to achieve there's     also some testing in Europe that we've been looking at using in Germany looking for t-cell activation you know and again     the traditional Western blot Eliza to Western blot CDC two-tier testing again     the bacteria is so smart and can evade that frequently those antibodies aren't there when they should be I always tell     people that you know this when we look at the at these tests and we look at you know what you're reporting to me about     your health you know this could be construed as scary or overwhelming or wow I had no     idea that was so much wrong with me etc when I see all that data I get excited     you know because here's somebody who has been suffering for years and years with no answers and     now we have a map and we have a road map of you know things to try things to work     on yeah so first phase of treatment for me is always trying to optimize the     patient's immune system and usually that focus is on their gastrointestinal system so you know we do comprehensive     stool testing with a couple of different labs simultaneously we always frequently     do almost always do SIBO breath testing for small intestinal bacterial overgrowth and and at that point almost     always my first intervention is supportive and also antimicrobial     protocol for the gut for the gastrointestinal system and along with     that I will address certain key you know nutrient deficiencies hormone imbalances     whether thyroid or adrenal I see those as you know adrenal dysregulation thyroid imbalance as very core pieces     these are all like the the legs of the stool if you will that you know we can get that stool solid and get the person     balanced on these core levels everything else that we're going to try to do is going to be more effective you know     we're gonna quiet down immune system hyperactivity quiet down inflammation     get there detoxification systems working better you know and almost always the     pit person feels better from these protocols without ever directly addressing you know what we might think     might be some hidden infections lurking in the background and my take on that is that you know we know from this really     exciting field on you know microbiome microbiota gastrointestinal ecosystem in     all of our body this you know bacterial microbiome balance that we carry we know     that you can make pretty impressive gains on     the immune function on the ability to control inflammation and to quiet down     autoimmune activation so those are really key pieces and with that you know     dietary intervention is our foundation as well using low dose naltrexone is is     definitely a growing part of my practice and I think at this point definitely the     majority of my patients are either on it or we've tried it and for some reason you know a small percentage of people     decide that it's not not something they want to be taking but and it's also I'm     noticing that I'm using it earlier and earlier in the in the treatment you know previously it was something like I would     see the patient I'll talk to him about some options I would send them out with a bunch of testing they would come back in a couple of months we'd go over the     results and particularly with the SIBO small intestinal bacterial overgrowth had been using a lot of low dose     naltrexone because of its you know activity as a pro motility agent to help     you know with gastrointestinal motility and these patients who come in are kind     of like this almost it's like soup of inflammatory mediators you know they're     they're they're really overloaded with triggers and they're not able to you     know clear out the toxins etc and so the the any interventions that we can do     that help to start lowering that inflammatory load I find beneficial across almost no matter what is     happening for them you know so I think that that the the low dose naltrexone in     terms of its ability to to modulate that inflammation to kind of reset that     autoimmune activation is really really helpful yeah there's absolutely a denial and and     a controversy as well as a rise in the public media of in terms of awareness around around Lyme disease and to be     very honest with you it really confuses me I don't understand it I don't understand you know you know you     know I went through my medical training through my medical school and my residency and you know almost minimal exposure was     given to these infections other than the very mainstream you know so you have Lyme disease you get your bull's eye     rash and your knee swells up and take your two weeks of antibiotics and you're fine and you know so it really was a and     many of us it happens this way where it becomes a personal issue either a friend or a family member or sometimes a     practitioner themselves forces them to kind of dig in deeper so since my     specialty is treating immune immune brain and got issues I treat a lot of     people with autoimmune diseases neurodegenerative disorders I treat autistic spectrum disorders     chronic infections of all types including chronic limes I do treat a lot     of patients with Lyme disease I use the same protocols that I use to treat my patients with autoimmune disease it     autoimmune disease is an epigenetic disease with triggers Lyme disease has     very similar profiles very similar triggers very similar things that make     it worse and better and very similar responses to patients with autoimmune     disease and so I find a very good success rate in treating patients in a similar manner researchers have said     that dietary factors that change the microbiome might be a cause or     contributing factor to up to 90% of human diseases I see that dietary     changes help people almost universally so dietary changes are a very powerful     aspect every patient that I see sees a nutritionist that's one of the important     cornerstones of treatment whether it's chronic Lyme or any other chronic     disease process research has also shown that changing your diet changes your     microbiome within about four days your microbiome is all the bacteria and     microorganisms that in and on your human body but mainly we're talking about when we mentioned     the microbiome were mainly talking about the bacteria and microbial Biot a there inside your gastrointestinal tract as     that microbiome changes with diet it literally changes your human genetic     expression for either disease or health often times poor diet means not just     that you're not getting the nutrients that you need but that you're feeding your body hormones chemicals things that     aren't really food human bodies are designed made grown to digest food our     body knows how to do that I can tell you that people of all types that have a     poor diet that they do have and especially when they're not willing to     fix it themselves that they do have poor outcomes and when I have patients that     either can't or won't change their diet they are not the patients that I have that heal so one of the first things     that I say in regards to diet is eat food that's just food no additives preservatives chemicals hormones     genetically modified organisms if you are eating a food if it comes in a     package you should be able to understand every ingredient that's on that package it should be something that you can buy     at your store and add to your food at home so for instance high-fructose corn     syrup is something that we've heard is a natural ingredient but it's not something that you can buy at the store     and add to your food so it shouldn't be in your foods and then adding in there     should always be more vegetables than proteins on your plate for any given     meal and lots of times that's something that we're getting backwards in the United States and I think in most     industrialized nations and then breads and pastas and these nearly non foods     are things that take up a third or a half of our plate very often and these     are things that don't contain very much very many sources of nutrients but     they do have very detrimental effects effects both on the microbiome and on     the intera sites which are the cells of the wall of the gut Lyme disease is     something that has become almost as scary as cancer to some people because     it seems like there's no hope of recovery and there are people who stay sick for years and even decades with the     right treatment I believe that everyone with Lyme can be treated I typically     tell my patients with Lyme to expect a six-month to 2-year recovery period depending on all the aspects that are     going on with their health everything that we have to treat how they respond and how compliant they are with their     treatment regimen and what's happening around chronic disease states like     autoimmune disease neurodegenerative disorders chronic infections like Lyme I really feel that our medical system     either oversimplifies or over complicates things Lyme disease is     unique in that it it does kind of hide from our immune system but it does that     through several chemical mechanisms that are being better and better to find one     of the things that Lyme does that's fairly atypical as far as we know is that it's a pleomorphic organism that     means it changes shapes so it's it's a shapeshifter inside of our system as it changes     shapes the antibiotics for instance only treat one of the three forms that Lyme     takes whilst in California one name kept     cropping up dr. Kent holtoff he agreed to meet me at his office in Los Angeles     his forthright views hold so much substance and as a came practitioner and user of LDN it was important we hear     from him the whole world is suffering from this immune dysfunction and it's     the basis of so many illnesses why this worked for so many illnesses and and so     with you know all everything from chronic stress gluten you know demos     autoimmune diseases chronic infections gut issues all these things are causing     the immune system to be dysfunctional and so you have two sides from you system you have th1 and th2 in general     so th one gets stuff inside the cell th two gets stuff outside the cell so     you need to be balanced what happens in so many different illnesses even with just aging your th one goes down here th     two goes up so now you can't fight these intracellular infections you get reactivating virus such as you know the     herpes virus shingles the chickenpox comes out and you can't fight those infections but you have too much     inflammation going on so increase heart disease autoimmune disease and then when     you get the autoimmune disease or allergy that makes it worse so it's continually driving the body in this     direction and causes so many things and which is why we see with for instance Lyme disease almost everyone if not     everyone has autoimmunity they have we're finding now antibodies to the brain which they're calling you     know and basically it's a version of pandas which is normally childhood illness where the the strep infection     the body cross reacts in the text the brain that's going on in the majority of Lyme patients that we are testing and so     one the key to for treating Lyme disease the key is treating the immune system if     you fix the immune system you get rid of Lyme disease most people have Lyme disease have no symptoms that's the     problem and when you look at a lot of these tests and they come out but the FDA will say oh that's inaccurate     because people who have no symptoms turned up positive but guess what five years ten years later when they     have a significant stress family basically death in the family a divorce     emotional trouble seems to really be able to trigger it but also let's say a car accident or another infection or a     cancer all of a sudden boom it just hits now the body can't suppress that line it     comes out suppresses the immune system or all these other infections so which is why Lyme patients they have usually     you know five ten fifteen twenty other diagnoses which aren't necessarily     incorrect but it's what's what's causing it and it becomes a chicken or the egg saying what causes so you have to treat     all those different components so now the body can actually fight the infection and that question comes up     it's very good question what is Lyme disease and people say well to infection     by you know the Borrelia burgdorferi up but it's it's a lot more than that and     we're finding the problem is is that is it usually is asymptomatic or stack-up     there's so many different forms of it that some people that get Lyme when we call Lyme disease typically thought of when people get acute line they get     bitten by a tick they you know week or so later they get flu-like feelings and a rash and they have a typical syndrome     treated with antibiotics that goes away but that's a fraction of the people that have chronic Lyme disease chronic Lyme     disease is very different it basically you usually don't know when you got it majority people have no idea they've     never been a really high risk for a tick infection for a tick bite and they go     along no problem all of a sudden middle-aged they start getting stressed that immune system     start shifting then all of a sudden they get hit like oh my gosh what's going on I've been diagnosed with fibromyalgia     been diagnosed the chronic fatigue syndrome so it affects almost every cell in the body and it's very slow growing     very resistant and which is why there's all these controversies and and they'll say for instance well if it's Lyme     disease you treat it for three weeks of antibiotics or they're not better than it can't be Lyme disease and we had the     same thing with chronic fatigue syndrome where we would have patients we published our studies we had 500     patients come in they had seen on average 7.2 physicians without any     improvement before seeing us after five visits they basically had dramatic you     know some dramatic significant and in any improvement in and in their overall     sense of well-being was hugely significant and their energy level doubled and all this and which is with     patients would say they chose their doctor and they say well you obviously didn't have chronic fatigue syndrome because it's incurable     it's very good to be skeptical and that's what we want we want healthy medical debate but unfortunately that     hardly ever happens anymore it's become so polarized so political are you with     us or against us and you know I'm not married to any treatment or any diagnosis if you know basically patient     comes in all the symptoms fit lyme disease okay to either diagnose them with 42 different diagnoses or does this     make sense they turn out positive on tests you give them treatments they get better I believe it's Lyme disease if a patient     goes to a doctor and that doctor can't get her better he feels terrible but how     can he feel better about him or herself they say I don't believe that person's help well I don't believe it's a real     illness so either now and if they believe Lyme now they're gonna have to go back and spend how tons of hours     trying to learn about how to treat Lyme and treat this patient and they don't have time they don't get paid extra for     doing that they just you know they basically paid colds and flus but you have one complicated Lyme patient that     involves the entire system in the body that's the problem who's supposed to take care of this person and you're just     clogging up their their time so it's so much easier for them and serves them     well emotionally financially to say this doesn't exist it takes on average 17     years for a proven concept accepted of mainstream medicine they found well again why is that     and one doctors don't read medical journals they don't they don't have time there's no incentive to do it why should     they find out some new treatment everything's dictated by the insurance companies so you basically     doctor goes in house but doctor make the most money you see as many pages he can make if quickest diagnosis and get that     medication that patient get them out some of this controversy in line glum driven from a financial standpoint by     insurance companies saying hey we're not going to pay for this absolutely Lyme is     a horrible illness and it's horribly expensive because especially they had it     for a long time it takes a long time to get better on most cases and and then     where they look at you know again you're gonna believe the data that supports what benefits you so the insurance     companies look at the data that said three months of antibiotics wasn't didn't make the patient significantly     better all there are some that show it some that that it didn't work you know my responsible isn't long enough and we     can do a lot of other things that do help the patient but they use those say okay we can deny treatment and and you     hear yes that Lyme disease your mimics other illnesses syphilis was known as the great imitator it imitates other     illnesses and whether that is a smart thing you know that oh it's it's gonna     try to show you it's something else I think it's more it's really fits with the pathophysiology of the illness and     that so many illnesses are driven from the same underlying problem which is the     abnormal immune system and we're finding I mean now it seems like everybody's sick and though the rate of chronic     fatigue syndrome fibromyalgia asthma diabetes all these things our immune     dysfunction that is at the base again that teach one teach two is like this people get more cancers more diabetes in     the ability to lose weight these infections are driving that so you're getting all those saying but basically     symptoms and I even we're finding you know what's the symptom of Lyme for us one is type two diabetes usually Babesia     so a co infective Lyme so it's this chronic inflammation that causes so many     things and it began it becomes a chicken or the egg the inflammation suppress the pituitary which then causes low hormone     so now you get hyperthyroidism which now there's no energy there's no energy for the immune system that goes down body     can't fight the infection gets worse and worse and that's why we look at it such a multi system illness so you had people a lot     of people have basically a gene that clots very quickly at some point in our     ancestry that was good you could whatever you get cut or bitten by something you clot it quickly you're     gonna survive now it's a negative we're living longer basically you people have     more strokes and heart attacks and we're finding with Lyme you get this a number of different things is you get immune     activation of coagulation so the body lays down fibrin along the vessel not a     clot but fibrin and what happens oxygen now cannot get into the cells very very     easily which normally takes two seconds to get it takes up to two minutes so the cells are starving for oxygen and we do     a little test for that and people will complain of air hunger is that if people you take a breath hold out blow out all     your air and then you check a pulse ox now a normal person as the as the oxygen goes in the lungs in and then into the     capillaries that into the cell now that that oxygen level will drop because nothing replacing it with Lyme patients     majority of you see that doesn't drop so it's not going anywhere to staying in     the blood and what we're also finding that so many Lyme patients have autoimmune things like antiphospholipid     syndrome and then so you start getting this overlap of autoimmunity hyper quiet     ability and things causing this whole array of symptoms so it's why so there's     so many different presentations of line but I'm just noticing it seems that every person I talked to either them or     a family member has got some serious illness that the first day I think of is     Lyme you know they got chronic fatigue syndrome fibromyalgia they can't get out bad they have MS and it's just exploding     and and people you'll say it themselves that why is everyone sick now even the     obesity and there's good evidence that obesity is infectious so I think all these things are a problem and the     government you know it's when do you basically you know pull the cord and say oh my gosh we have an emergency here and     the question you know why don't some patients respond to antibiotics I think it's it's certainly multi-factor     Oriol and the key determinate is the immune system so if you have an intact     immune system or good th1 th2 isn't elevated yet and you get Lyme you know     you can treat that if you get antibiotics on board fast enough good chance you're going to get get rid of     that infection you know and and so what having a question comes how do you treat a Lyme patient and and that's one thing     you look at the patient's immune system you tell if it's cute chronic you know we do a large panel of tests which are     becoming more and more difficult to get because insurance companies but we can pretty much pick out a Lyme Khurana     fatigue syndrome fibromyalgia patient 80% of the time and unlikely how severe     their symptoms are so we can actually tell those things from a blood test without talking to the patient so people     say they don't believe in these things say well we can you know put the plate with just their labs we can pick them     out hey they're not making it up so so really again how do you treat chronic     Lyme you know antibiotics certainly may be a part but we found once you reach that threshold on their own they're     likely not going to be successful you have to do other treatments if you don't fix the immune system the patient     doesn't get better so an LVN basically does what we want it to do is     we'll ship that teach one teach two it will lower inflammation but increase     that good immunity so your body can now have a chance to fight those intracellular infections yeah and and     there's so many therapies for for Lyme patients that work and there's so many therapies that don't then but you know     there's some oftentimes they're the same treatments one patient oh my gosh this was amazing other person says that     didn't do anything for me and it depends on the person the strained co-infections     we're in the stage of treatment they are we'll find paisas tried something early on it didn't do anything for them but     after you make progress that same treatment is profoundly effective for them it's in in terms of financial     issues with Lyme and every other and you look at the model is now you     know it's basically currently you don't need a medication until you're sick enough and and you know basically so 90%     of the healthcare dollars are spent in the last five years of person's life and that's where all the money is you know     no one wants to spend it earlier which we much more cost effective but insurance companies don't want to do     that you say well they'll save money in the long run because but you'll probably with us different insurance companies they spent the money to save it for     someone else but it is a problem this is not an illness for the poor it is very     difficult to get treatments you know the the best treatments are expensive     no no doubt and it is in a knowledgeable patient and it's interesting where I     encourage patients go on the internet look up all the information you can come back and we'll talk about it you know     and with so many doctors if a patient does that walks in with articles says I've been reading on go they stopped     reading of Google you don't trust me you know is if you find a dark like like that run and unfortunately most patients     with Lyme know more about Lyme than their doctor does I think Lyme is a scourge of humanity it     is going to become one of the worst problems of health for the entire world     at some point unless something dramatic happens the key is the immune system     that is the one thing that's going to make or break is the success or failure     of your treatment LDN is one of a number of treatments but is a great starting     point because it is cheap extremely safe and effective does it work for everyone     no nothing does but treating the immune system is the key to successfully     treating Lyme to further understand the testing procedure we paid a visit to dr.     Armin Schwarz back in osburgh just outside Munich in Germany I'm elapses highly specialized in tick     borne diseases testings and also advice when the results are finished     tick-borne diseases are very common in the world we know that ticks are full of pathogens     of different bacteria and my laboratory can test blood samples from infected     patients for different bacteria we named them Borrelia burgdorferi it's the main     bacteria in the ticks and then we have also other co so-called corn affections     co-infections are Bartonella le here Anibal asthma Babesia Rickettsia and my     laboratory is doing testings from blood samples from all patients all over the     world so we find out if there are immune answers against different bacteria or     not in the blood of patients we have different strains against Borrelia burgdorferi we know actually it's over     eight different strains which can make patients sick the three very common     strains in the world in Europe especially are Borrelia burgdorferi sensu stricto and Borrelia burgdorferi     Guarini i and perlier bhakta Frei of Sealy I in USA is a little different we     have more Borrelia burgdorferi sensu stricto but all over the world we can     find a lot of other different subspecies we name that and one of the most common     subspecies is perlier booked off right Guarini i which makes the neurological problems with symptoms     we know that Borrelia burgdorferi is in up to 50% of infected ticks so patients     or people got bitten by the tick and the tick the tick is full of this bacteria     then it can be transmitted into the body of people and then the question is how     strong is your immune system Ostrom is your natural immune defense against this we name it pathogen pathogen Borrelia     burgdorferi and if you immune system is strong enough you can defeat it on a natural way if not you can get symptoms     symptoms for Lyme disease are at the beginning of bullseye bullseye rashes are also named     everything are microns and but it's not in all of the patients we have just 50     page percent of the patients or the people who got infected they really got this bullseye rash or erythema migrans     so fifty percent you cannot diagnose because they don't have this bullseye rash and also twenty percent can get     summer flu after tick bites so it's very important to get some to ask a patient     patient did you get some summer flu after tick by because this is a sign     foreign current infection with Lyme disease in this case we name it stage     one of the infection if Borrelia is coming into your body by a tick bite in a second step it can move around all     over your body and can infect each organ system in your body for example it can     inflame your brain it can inflame your joints your muscles also it can inflame     you kidney your liver your eyes you can move everywhere in your body and this     means a local inflammation by a bacteria in your body which makes symptoms the     question is which symptoms do you have after tick bite a lot of patients I've     seen I think meanwhile several hundreds personally I have seen in my office and     I found that a lot of patients they developed chronic fatigue syndrome immediately they got very tired after     tick bite they call it all the burnout syndrome doctor they say doctor I have a     burnout syndrome all the patients they develop neck pain and headache and especially we have a tick bite was on     the site on this side where the tick bite was the patients develop one of the first symptoms neck pain headache and     the next can be also my current joint pain it can be also another different     like writers it can be a different symptom like neurological symptoms     sensitivity problems burning hands burning feeds and loss of sensitivity     concentration problems brain fog so Borrelia can do every symptom in your     body you can imagine the best way to get notified means prevention so in     preparation the better you are prepared if you have for example your clothes are     very important that there is no place where the tick bite can happen with you     for example also if you walk in the middle of the trails very important not     to lean on trees not to walk outside the safe situation or to sit in the crest so     the exposure is very important and the consciousness the tick bite doesn't     happen immediately you have also the chance after coming back from outside from auto activities to inspect yourself     you can inspect your hair are your ears everywhere you go under a shower you     look everywhere you look at your back also for children were important to look everywhere we're a tick bite can be     because prevention means everything the tick is not biting immediately you the tick needs time to bite it's not done in     two seconds so we have time no panicking but prevention prevention prevention the     probability to get an infection with Borrelia burgdorferi it's not such a     high risk but the risk is there and if you estimate ten tick bites for example     you get one time transmission statistically of poorly booked off right but that doesn't mean that you get sick     by the infection nevertheless we have numbers from your USA and in America we     have around 400,000 new infections each year and in USA the CDC they said some     years ago or we have just 30,000 that means we have more than tenfold higher     infected people in USA what does that mean if you look at one year and     you do a Luger in ten years you have in ten years F tenfold 400,000 of maybe     four million infected patients and that's a huge number we have more     problems with tick bites why because the outdoor behavior is different of the     people we are forced to go outside to do some sports activities because we are     sitting the whole year in our offices so we need more movements outside and but     the risk is outside and also very important the climax is changing somehow     we have more more ticks all over the world the earth is heating up so the ticks get active when it's for up to     five centigrades and although we've a flam Izzie's cases in Greenland or in     Alaska or in northern Norway so we have more and more ticks everywhere around     the world but although the testing is better now we find more infected people     by better testings which didn't exist 20 years ago we have better testings for it     we find more infected people and the consciousness is better now            

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